Review - Document Details


Review - Reviewer's Assessment

1. Short summary / abstract
This is a simple guide which explains what Clostridium difficile is and gives very brief background information on the epidemiology. The clinical picture is described and there is an explanation of who gets C. difficile, how it spreads, the causes, diagnosis and different typing to identify the more virulent strains.
Prevention and control is outlined under the headings: -
Prudent antibiotic prescribing
Isolation of patients and good infection control nursing
Enhanced environmental cleaning
The document is primarily aimed at professionals but would make a useful guide on which to base leaflets for patients and their relatives.

2. What question is the document addressing?
The guide explains what C difficile is, how it developed, ways in which it can cause infection and basic prevention and control practice.

3. Type of study
Basic Guidance leaflet

4. Methods valid & appropriate?

Appropriate for healthcare associated general article/basic guidance leaflet.

5. Results / recommendations reliable?
Yes - Appropriate for healthcare associated general article/basic guidance leaflet.

6. Any major problems and biases?
Links to other key documents on Clostridium difficile infection and surveillance could have been usefully included.

7. Any other important / relevant studies which confirm or contradict?
1. Clostridium Difficile Infection – Prevention and management. A Report by a Department of health/Public health Laboratory Service Joint Working Group (1994)
2. National Clostridium difficile Standards Group Report to the Department of health. The Journal of Hospital Infection (2004)56; 1-38 (Supplement 1)
Also available from the Health protection Agency Website

8. Keywords
clostridium difficile antibiotic associated diarrhoea colitis infection control Type 027

Reviewer's Details:

Name:Sue Wiseman
Post:Nurse Consultant –Infection Control, DH
(Society / Organisation / Advisory Committee):
Member Advisory Committee on Dangerous Pathogens
Health Protection Adviser Royal College of Nursing P/T
Member Infection Control Nurses Association

*** Note: These are the views of a professional expert rather than an official statement from his or her society, organisation or advisory committee.

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