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British HIV Association (BHIVA) Guidelines - HIV and Chronic Hepatitis: co-infection with HIV and Hepatitis B virus infection

AbstractThere are many minor changes in these guidelines updated in 2004. The main changes include: reformatting in the style of the ART guidelines, treatment algorithms added, new, clearer definitions of when to treat and with what, high CD4: ideally treat according to liver biopsy result. Options are to use interferon if HBeAg +ve (non-cirrhotic) and abnormal LFT or adefovir in those who are HBeAg +ve or HBeAg –ve and HBV-DNA >104 copies/ml (>103 if cirrhosis); Low CD4 requiring ART: treat according to HBeAg status and HBV-DNA (as above). Can use tenofovir alone as part of HAART. 3TC/FTC are only recommended in combination with tenofovir. Updated clinical trial evidence and references. New information on investigations and vaccination.
Date of last revision by publisher10/01/2004
Date of last review by us05/12/2005
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