Resource Details


Processing Swabs For Group B Streptococcal Carriage (BSOP 58)

Standards Unit; Evaluations and Standards Laboratory; Centre for Infections
AbstractThis SOP describes the processing of specimens from pregnant women for carriage of Group B streptococci (GBS). Recognising that it is not recommended in the UK to screen routinely for GBS (Royal College of Obstetricians and Gynaecologists 2003; National Institute of Clinical Excellence 2003; HPA 2004), this SOP provides a standardised method for culture where clinicians decide to investigate specific patients with conditions considered to confer a high risk of infection. Commercial tests detecting the GBS group antigen extracted from vaginal swabs based upon latex agglutination, ELISA, immunofiltration, immunochromatography, optical immunoassay and other methods are available. However, the evidence accumulated has shown that the sensitivity and specificity of direct antigen tests is inferior to that of culture methods.
Date of publishing06/26/2006
Date of last review by us01/06/2011
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